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CD86 抗体 (PE)

This anti-CD86 antibody is a 大鼠 单克隆 antibody detecting CD86 in FACS. Suitable for 小鼠.
产品编号 ABIN316890
发货至: 中国

Quick Overview for CD86 抗体 (PE) (ABIN316890)

抗原

See all CD86 抗体
CD86

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD86 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

PO3
  • 特异性

    This antibody recognises CD86 (B7-2). The PO3 clone has been reported to block some co-stimulatory functions of CD86.

    产品特性

    Synonyms: CD28LG2, B70, FUN-1, BU63, T-lymphocyte activation antigen CD86, Activation B7-2antigen, CTLA-4 counter-receptor B7.2

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    免疫原

    Mouse B-cell line, BCL1.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: 1/10.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Reconstitute with 1.0 mL distilled water

    浓度

    0,1 mg/mL

    缓冲液

    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD86

    别名

    CD86

    背景

    CD86 is an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse, CD86 is expressed at high levels on peripheral blood monocytes, dendritic cells and at low levels on resting B and T-lymphocytes. Expression of CD86 on these cell populations can be increased upon activation. CD86 has been identified, along with CD80 (B7-1) as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86

    基因ID

    12524

    UniProt

    P42082

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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